Translational Medicine

Installable Claude components bridging discovery and clinical application — clinical-trial tooling, biomarker discovery, patient stratification, real-world evidence, EHR-aware agents, and regulatory-document assistants.

10x Genomics Cloud MCP

MCP server · 10x Genomics · GA · verified: degraded · security: caution

Conversational orchestration of 10x Cloud single-cell, immune-profiling, and spatial-transcriptomics analyses.

ACMG Classification (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: caution

Classifies germline variants P/LP/VUS/LB/B under ACMG-AMP 2015 with ClinGen SVI specifications, Tavtigian Bayesian points, and calibrated in-silico thresholds

AWS HealthLake MCP Server

MCP server · AWS Labs · GA · verified: works · security: cleared

Apache-2.0 MCP server for AWS HealthLake FHIR datastores — CRUD, advanced search, patient-everything, and import/export jobs, with a read-only safety mode.

Adaptive Designs (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Plan group-sequential, sample-size re-estimation, seamless Phase 2/3 and enrichment trials with rpact/gsDesign, against FDA and ICH E20 adaptive-design guidance

AdisInsight Plugin

Claude Code Plugin · Springer Nature · GA · verified: degraded · security: cleared

Springer Nature AdisInsight MCP plugin surfacing drug-development pipeline, clinical-trial, and deal intelligence to Claude for repurposing and competitive scouting.

Adverse Event Detection (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that detects adverse-drug-event signals from FDA FAERS with disproportionality statistics (PRR, ROR, IC) and a 0–100 safety signal score.

Aging and Senescence Research (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA

ToolUniverse agent skill for geroscience — senescence markers, aging hallmarks, longevity GWAS, and senolytic target discovery with graded evidence.

Anthropic PubMed Connector

MCP server · Anthropic · GA · verified: works · security: cleared

Anthropic-managed NCBI literature search via PubMed and PubMed Central.

BGPT Paper Search (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server.

BLAST (Bio-MCP)

MCP server · Bio-MCP · GA · verified: works · security: caution

MCP server wrapping NCBI BLAST+ for nucleotide/protein similarity search and custom database creation, run locally over stdio.

Bayesian Trials (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Design Bayesian dose-finding, basket and platform trials with RBesT MAP priors, BOIN/CRM escalation and EXNEX borrowing, against current FDA Bayesian guidance

Benchling (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Benchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries.

BioBank Japan (Claude Science Connector)

Claude.ai Connector · Anthropic · GA · verified: works · security: cleared

East Asian biobank GWAS summary statistics from BioBank Japan (PheWeb); a source in the Human Genetics connector in Claude Science.

BioContextAI Knowledgebase MCP

MCP server · BioContextAI · GA · verified: works · security: cleared

Read-only MCP that unifies 14+ biomedical databases (Antibody Registry, UniProt, STRING, AlphaFold, KEGG, Open Targets) for immune and protein-context queries.

BioMCP

MCP server · GenomOncology · GA · verified: degraded · security: cleared

Unified biomedical lookup across PubMed, ClinicalTrials.gov, MyVariant, and OpenFDA.

BioPython (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Comprehensive molecular biology toolkit.

BioRender Connector

MCP server · BioRender · GA · verified: degraded · security: cleared

Scientific-figure assembly from the 50,000+ BioRender icon and template library.

BioServices (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Unified Python interface to 40+ bioinformatics services.

Biomni (Claude Skill)

Claude Skill · Stanford SNAP Lab · GA · verified: works · security: caution

General-purpose biomedical AI agent that plans and runs multi-step research workflows across genomics, drug discovery, and clinical analysis.

CAN-IMMUNE

MCP server · Li/Purcell Lab, Monash University · GA · verified: works · security: caution

Hosted MCP server over the CAN-IMMUNE cancer neoantigen database — mutant peptides, cell lines, tissues, and MHC-I binding predictions.

CDISC Data Handling (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: caution

Read SDTM XPT files, derive ADaM datasets with traceability, apply TEAE conventions, and validate for FDA submission with Pinnacle 21 or CORE

CIViC (Claude Science Connector)

Claude.ai Connector · Anthropic · GA · verified: works · security: cleared

Crowd-curated clinical interpretations of cancer variants from CIViC (WashU); a source in the Clinical Genomics connector in Claude Science.

CMS Coverage MCP (Anthropic Healthcare)

MCP server · Anthropic · GA · verified: works · security: caution

Anthropic-published MCP server over the CMS Coverage Database — Local and National Coverage Determinations for Medicare prior-auth, appeals, and policy lookup.

CMS data.gov MCP Server

MCP server · Clarify Health · GA · verified: works · security: caution

MIT-licensed MCP server over data.cms.gov — search, query, and export CMS public datasets (provider enrollment, hospital quality, spending) for healthcare analytics.

CNV Inference (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Infer chromosome-scale copy-number alterations from tumor scRNA-seq to separate malignant from normal cells and call subclones with inferCNV, copyKAT, Numbat and SCEVAN

CNVkit (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Detect somatic CNVs from WES/WGS/targeted BAMs (CNVkit v0.9.x).

COSMIC (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: caution

Query COSMIC for cancer somatic mutations, gene census, mutational signatures, drug resistance variants.

Cancer Genomics TCGA (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill for TCGA/GDC cancer genomics — cohort construction, clinical metadata, somatic mutation frequencies, CNV, survival analysis, and OncoKB variant interpretation.

Cancer Variant Interpretation (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that turns a gene + somatic variant + cancer type into an evidence-graded precision-oncology report with therapies, resistance, and matching trials.

Cell Line Profiling (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that ranks cancer cell lines for an experiment by cross-referencing DepMap, Cellosaurus, COSMIC, and PharmacoDB.

Cellxgene Census (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Claude skill for querying the CZ CELLxGENE Discover census — 50M+ standardized single-cell observations across 1,000+ datasets via TileDB-SOMA, with AnnData / Scanpy integration.

Certus Drug Information MCP Server

MCP server · Aditya Damerla (zesty-genius128) · GA · verified: works · security: caution

MIT openFDA MCP server focused on drug shortages, recalls, labels, and adverse events — with a zero-install hosted endpoint and batch analysis across up to 25 drugs.

Chemical Safety (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill for chemical hazard and toxicology assessment via ADMET-AI, CTD toxicogenomics, AOPWiki, GHS/IARC classification, and regulatory safety data.

ClinGen (Claude Science Connector)

Claude.ai Connector · Anthropic · GA · verified: works · security: cleared

Expert-curated gene–disease validity and variant clinical significance from ClinGen; a source in the Clinical Genomics connector in Claude Science.

ClinPGx (PharmGKB) (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations …

ClinVar (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations.

Clinical Decision Support (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports …

Clinical Note Extract (Anthropic Healthcare Plugin)

Claude Skill · Anthropic · GA · verified: works · security: caution

Anthropic Claude skill that extracts structured, validated records from unstructured clinical notes with span-level provenance and explicit null handling.

Clinical Reports (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries).

Clinical Trial Design (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that scores trial feasibility across endpoint, population, comparator, effect size, duration, and regulatory pathway using precedent trials.

Clinical Trial Matching (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that turns a molecular profile into ranked trial matches across ClinicalTrials.gov, EU CTIS, and ISRCTN with evidence tiers.

ClinicalTrials.gov MCP Server (cyanheads)

MCP server · cyanheads (Casey Hand) · GA · verified: works · security: cleared

Apache-2.0 MCP server over the ClinicalTrials.gov v2 API — trial search, full study records, outcomes / adverse-event extraction, and patient-to-trial matching. Hosted public instance available.

Composer

Plugin · Scripps AI Enablement · Beta · verified: works · security: cleared

Turns a plain-language scientific problem into a grounded, runnable Claude solution composed from this catalog, reusing recipes and, for open-ended goals, assembling a multi-agent system from those same components.

Consensus Plugin

Claude Code Plugin · Consensus · GA · verified: degraded · security: cleared

Consensus.app MCP plugin bringing AI-powered scientific literature search and evidence synthesis into Claude across all research areas.

Cortellis Plugin

Claude Code Plugin · Clarivate · GA · verified: degraded · security: caution

Clarivate Cortellis MCP plugin surfacing global drug-pipeline, clinical-trial, regulatory, safety, and deals intelligence to Claude for competitive scouting and regulatory work.

DDInter (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: caution

Query DDInter drug-drug interactions via REST API (1.7M+ interactions, 2,400+ drugs).

DailyMed (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Query FDA drug labels (DailyMed) via REST API.

Database Lookup (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Search 78 public scientific, biomedical, materials science, and economic databases via REST APIs.

DepMap (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Claude skill for querying the Cancer Dependency Map — CRISPR Chronos gene-effect scores, PRISM drug sensitivity, mutation, expression, and CN data across cancer cell lines.

Drug Mechanism Research (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that traces a drug’s mechanism from primary target through off-targets, pathways, FDA label, and pharmacogenomics.

Drug Pipeline MCP Server

MCP server · DasClown (community) · GA · verified: degraded · security: caution

MCP server aggregating clinical trials, FDA/EMA approvals, safety data, and labels into source-traceable drug pipeline intelligence — no predictions, every output cites its primary source.

Drug Regulatory Research (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA

ToolUniverse agent skill for jurisdiction-aware approval status — UNII identity, ATC/EPC class, Orange Book patents and exclusivity, generic availability, label parsing.

Drug Repurposing (Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that finds drug-repurposing candidates via target-, compound-, and disease-driven strategies with mechanism and feasibility scoring.

Drug Research (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that compiles a comprehensive drug dossier — mechanism, targets, ADMET, trials, FAERS safety, pharmacogenomics, and approval history.

Drug Target Validation (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that scores a drug target 0–100 across genetic, druggability, safety, and clinical-precedent gates with a GO/NO-GO recommendation.

Drug-Drug Interaction (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: caution

ToolUniverse agent skill that assesses drug-drug interactions via CYP/transporter pharmacokinetics, pharmacodynamic overlap, and 0-100 clinical risk scoring.

DrugBank MCP Server

MCP server · openpharma-org (community) · GA · verified: works · security: caution

Community MCP server exposing a local DrugBank SQLite (17k+ drugs) with 16 query methods for repurposing, target lookup, interactions, and structural similarity.

EMBL-EBI OLS (Claude Skill)

Claude Skill · Google DeepMind · GA · verified: degraded · security: cleared

Resolve and navigate biomedical ontology terms (GO, MONDO, HP, CHEBI, CL, UBERON, EFO, …) across 250+ ontologies via the EMBL-EBI Ontology Lookup Service.

Effect Measures (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Compute OR, RR, RD, HR and NNT with calibrated confidence intervals, and report marginal versus conditional estimands per FDA 2023 covariate-adjustment guidance

Ensembl MCP Server

MCP server · effieklimi · GA · verified: works · security: cleared

MCP server over the Ensembl REST API for gene/transcript lookup, sequence retrieval, variant consequences, comparative genomics, and assembly lift-over.

FDA MCP Server (OpenPharma)

MCP server · OpenPharma · Beta · verified: works · security: cleared

MIT MCP server over the FDA Orange Book, Purple Book, and openFDA — patent-cliff forecasting, therapeutic equivalents, and biosimilar interchangeability.

FinnGen (Claude Science Connector)

Claude.ai Connector · Anthropic · GA · verified: works · security: cleared

Finnish biobank GWAS summary statistics across thousands of endpoints from FinnGen; a source in the Human Genetics connector in Claude Science.

Fraud Detection (Anthropic Healthcare Plugin)

Claude Skill · Anthropic · GA · verified: works · security: caution

Anthropic Claude skill that screens Medicare/Medicaid claims for fraud, waste, and abuse, producing ranked, fully-cited investigation referrals for SIU teams.

GWAS Catalog (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

NHGRI-EBI GWAS Catalog REST API for SNP-trait associations from published GWAS.

GWAS Drug Discovery (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that turns GWAS-significant loci into druggable targets and repurposing candidates via fine-mapping, tractability scoring, and drug matching.

GWAS-MCP

MCP server · ZaEyAsa · GA · verified: works · security: caution

Single-install MCP server exposing 30+ tools across 14 biological databases (UniProt, Ensembl, ClinVar, GWAS Catalog, STRING, AlphaFold, KEGG, Open Targets, OMIM) for variant-to-target research.

Gene Liability Evaluation (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA

ToolUniverse agent skill that scores the human safety liability of inhibiting or knocking out a gene across five evidence dimensions.

Gene Ontology MCP Server

MCP server · Augmented Nature · Beta · verified: works · security: caution

Query GO terms, annotations, and enrichment inputs from the Gene Ontology; part of the Genes & Ontologies connector in Claude Science.

GlyGen MCP Server

MCP server · GlyGen · Beta · verified: degraded · security: caution

First-party remote MCP server over GlyGen’s integrated glycan, glycoprotein, biomarker, and disease data — protein, site, glycan, biomarker, and disease summaries.

Human Protein Atlas MCP Server

MCP server · Augmented Nature · GA · verified: works · security: caution

Query the Human Protein Atlas — tissue/blood/brain expression, subcellular localization, cancer markers, and antibody validation/staining data.

Hypothesis Crucible (Claude Plugin)

Claude Plugin · Scripps AI Enablement · GA · verified: works · security: cleared

Agentic cross-corpus hypothesis generation — mines typed knowledge fragments from literature, structured databases, and raw experimental data, bridges them Swanson-style into novel connections, then runs a falsification gauntlet that aggressively rejects non-novel, ungrounded, contradicted, or implausible ideas, emitting only survivors with cited support and a discriminating experimental test.

Hypothesis Generation (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Structured hypothesis formulation from observations.

ICD-10 Codes MCP (Anthropic Healthcare)

MCP server · Anthropic · GA · verified: works · security: caution

Anthropic-published MCP server for ICD-10 diagnosis and procedure code lookup, sourced from CMS and CDC, for medical coding and claims workflows.

ISO 13485 Certification (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems.

Imaging Data Commons (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index.

Immunogenicity Scoring (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: caution

Rank neoantigen and epitope candidates by likely T-cell response using NeoFox features, PRIME2.0, BigMHC-IM, the fitness model and pVACtools tiering

Immunotherapy Response Prediction (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that predicts immune-checkpoint-inhibitor response by integrating TMB, MSI, PD-L1, HLA, and immune gene expression into a 0–100 score.

Indication Dossier (Claude Skill)

Claude Skill · Anthropic · GA · verified: works · security: cleared

Anthropic agent skill that compiles an indication/target dossier by orchestrating Claude Science connectors (Open Targets, ClinicalTrials, literature).

Lesion-Symptom Mapping Guide (Claude Skill)

Claude Skill · Awesome Cognitive and Neuroscience Skills · GA · verified: works · security: cleared

Plan and run lesion-symptom mapping in patient cohorts — VLSM, multivariate SVR-LSM, disconnection and lesion network mapping

Literature Review (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.).

MSI Detection (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: caution

Calls microsatellite instability from WES/WGS/panel or cfDNA with MSIsensor-pro, MANTIS and mSINGS for dMMR, Lynch screening and ICI eligibility

Medical Terminologies MCP

MCP server · Sidney Bissoli · GA · verified: works · security: cleared

MIT-licensed MCP server giving Claude unified lookup and cross-mapping across ICD-11, SNOMED CT, LOINC, RxNorm, MeSH, and ATC.

Medicare MCP Server (OpenPharma)

MCP server · OpenPharma · Beta · verified: works · security: cleared

MIT MCP server over public CMS Medicare data — provider and prescriber lookup, hospital quality and safety measures, Part B/D drug pricing and formularies.

Medidata Connector

Claude.ai Connector · Medidata Solutions · GA · verified: works · security: cleared

Medidata’s clinical-trial MCP connector — query platform documentation (Rave EDC, Data Connect) and predict high-enrollment trial sites during protocol planning.

Mendelian Randomization (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA

ToolUniverse agent skill that uses genetic variants as instrumental variables to test whether an exposure causally affects a disease outcome.

Missing Data Sensitivity (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Run regulatory-grade missing-data analyses for confirmatory trials — MMRM, reference-based multiple imputation, tipping-point and pattern-mixture sensitivity

Momentum FHIR MCP Server

MCP server · Momentum · GA · verified: works · security: caution

MIT-licensed FHIR R4 MCP server with full CRUD, document ingestion/chunking, and Pinecone-backed semantic search over clinical records.

Monarch Initiative (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Monarch Initiative knowledge graph REST API for disease-gene-phenotype associations and cross-species orthology.

Multiplicity and Graphical Procedures (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Build the multiplicity strategy for confirmatory trials — graphical Bretz-Maurer-Hommel procedures, gatekeeping and Holm/Hochberg/Hommel — with gMCP and FDA 2022 guidance

MyGene.info MCP (BioThings)

MCP server · longevity-genie · GA · verified: works · security: cleared

Gene annotation and ID conversion across species via MyGene.info/BioThings; the Genes & Ontologies connector in Claude Science.

NPI Registry MCP (Anthropic Healthcare)

MCP server · Anthropic · GA · verified: works · security: cleared

Anthropic-published MCP server over the CMS NPPES NPI Registry — validate, look up, and search US healthcare providers by National Provider Identifier.

Neoantigen Prediction (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Identify tumor neoantigens from somatic variants with pVACtools for personalized cancer vaccines and checkpoint biomarkers, centering clonality, HLA LOH, expression, and validation tiers

NeuroKit2 (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Claude skill for biosignal processing — ECG, EEG, EDA, RSP, PPG, EMG, and EOG analysis including HRV, event-related responses, and multi-modal physiological insights.

OMOPHub MCP Server

MCP server · OMOPHub · GA · verified: degraded · security: cleared

Search, map and navigate 10M+ OHDSI OMOP vocabulary concepts (SNOMED CT, ICD-10, RxNorm, LOINC) from Claude without loading ATHENA locally

Ontology Lookup Service (OLS) MCP Server

MCP server · seandavi · Beta · verified: works · security: caution

Search and resolve terms across hundreds of biomedical ontologies via EMBL-EBI’s OLS; part of the Genes & Ontologies connector in Claude Science.

Open Targets (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Query Open Targets GraphQL API for target-disease associations, evidence, drug links, safety.

Open Targets Plugin

Claude Code Plugin · Open Targets · GA · verified: degraded · security: caution

Official Open Targets MCP plugin giving Claude GraphQL access to target-disease associations, drug evidence, and target-prioritisation scores.

OpenFDA MCP Server (cyanheads)

MCP server · cyanheads · GA · verified: works · security: cleared

Apache-2.0 MCP server federating the full openFDA API — drugs, food, devices (510k/PMA), veterinary, recalls, and shortages — with a public HTTP instance.

OpenFDA MCP Server (ythalorossy)

MCP server · Ythalo Saldanha · GA · verified: works · security: caution

MIT-licensed npm MCP server over the openFDA drug API — adverse events, safety/labeling, manufacturer lookups, and NDC resolution.

Owkin Pathology Explorer Connector

Claude.ai Connector · Owkin · GA · verified: degraded · security: cleared

Owkin’s Pathology Explorer agent — H&E whole-slide image analysis, cell-type detection, and tumour-microenvironment profiling — exposed to Claude as a remote MCP connector.

PLINK2 (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

GWAS and population genetics tool.

Paper Lookup (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: caution

Search 10 academic paper databases via REST APIs for research papers, preprints, and scholarly articles.

PathML (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Full-featured computational pathology toolkit.

Pharmacovigilance (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that mines FAERS adverse-event reports and FDA labels, computes disproportionality signals (PRR, ROR, IC), and assesses pharmacogenomic risk.

Power and Sample Size (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Size superiority, non-inferiority and equivalence trials for continuous, binary and survival endpoints, with FDA M1/M2 margin logic and CONSORT-ready justification

Precision Oncology (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that maps a tumor molecular profile to matched FDA-approved/investigational therapies, resistance mechanisms, and clinical trials.

PrimeKG (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: caution

Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological data including genes, drugs, diseases, phenotypes, and more.

Procedure Coding (Anthropic Healthcare Plugin)

Claude Skill · Anthropic · GA · verified: works · security: caution

Anthropic Claude skill that converts a clinical encounter’s documentation into claim-ready CPT and HCPCS Level II procedure codes the way a professional coder would.

Proto-OKN MCP Server

MCP server · SBL-SDSC (San Diego Supercomputer Center) · Beta · verified: works · security: cleared

Natural-language access to 30+ NSF Proto-OKN scientific knowledge graphs (SPOKE biomedicine, BioBricks chemical safety, more) via SPARQL, schema inspection, and cross-graph bridging.

PyDESeq2 (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Claude skill for bulk RNA-seq differential expression with PyDESeq2 — size factors, dispersion, Wald / LRT testing, BH-adjusted p-values.

PyHealth (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: caution

Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep …

PyTDC (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Claude skill driving PyTDC for Therapeutics Data Commons benchmarks — ADMET, drug-target / drug-drug interactions, drug response, molecular generation, retrosynthesis.

Rare Disease Diagnosis (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill for rare-disease differential diagnosis — HPO phenotype matching to Orphanet/OMIM, gene-panel prioritization, and ACMG variant interpretation.

Rare Disease Genomics (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill for rare-disease investigation — Orphanet characterization, HPO phenotypes, causative genes, GenCC validity, ClinVar variants, trials, and repurposing.

Revvity Signals AI Connector

Claude.ai Connector · Revvity Signals Software · GA · verified: degraded · security: cleared

Claude.ai connector giving natural-language access to the Revvity Signals electronic lab notebook and connected R&D data.

Scanpy-MCP

MCP server · scmcphub · GA · verified: works · security: caution

MCP server wrapping Scanpy so Claude can run end-to-end single-cell RNA-seq analyses (QC, clustering, DE, plotting) from natural language.

Scholar Gateway Connector (Wiley)

MCP server · Wiley · Beta · verified: works · security: cleared

Wiley remote connector for peer-reviewed scholarly content — 3M+ articles, 300+ Life Sciences journals.

Scientific Brainstorming (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Creative research ideation and exploration.

Scientific Critical Thinking (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Evaluate scientific claims and evidence quality.

SimpleITK (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Register, segment, filter, resample 3D medical images (MRI, CT, microscopy) via SimpleITK Python; DICOM, NIfTI, multi-modal.

Somatic Signatures (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: caution

Extracts and assigns COSMIC v3.4 mutational signatures from somatic VCFs with SigProfiler, MutationalPatterns, MuSiCal or HRDetect to read DNA-damage etiology

Subgroup Analysis (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Run subgroup and heterogeneous-treatment-effect analyses — interaction tests, RERI, causal forests, Bayesian shrinkage — against the Sun BMJ and EMA 2019 credibility criteria

Synapse.org Connector

MCP server · Sage Bionetworks · GA · verified: works · security: cleared

Discovery and metadata retrieval across Synapse-hosted biomedical datasets and consortium projects.

Target Research (ToolUniverse Claude Skill)

Claude Skill · Zitnik Lab (Harvard Medical School) · GA · verified: works · security: cleared

ToolUniverse agent skill that profiles a drug target across nine parallel research paths — expression, pathways, interactions, variants, druggability — into a cited report.

ToolUniverse

MCP server · Zitnik Lab (Harvard Medical School) · MIT Lincoln Laboratory · GA · verified: works · security: cleared

Harvard / MIT MCP server bundling 600+ vetted scientific tools — literature, chemistry, omics, clinical trials — for AI-scientist-style hypothesis exploration.

Treatment Plans (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Generate concise (3-4 page), focused medical treatment plans in LaTeX/PDF format for all clinical specialties.

Trial Reporting (bioSkills)

Claude Skill · GPTomics bioSkills · GA · verified: works · security: cleared

Produce CONSORT 2025 / ICH E9(R1)-conformant trial statistical reports: estimands, analysis populations, Table 1, MMRM, and multiplicity control

Tumor Mutational Burden (bioSkills)

Claude Skill · GPTomics bioSkills · GA

Calculates TMB from WES/WGS/panel data with Friends of Cancer Research harmonization, per-assay calibration, hypermutator tiering and blood TMB

WSO2 FHIR MCP Server

MCP server · WSO2 · GA · verified: works · security: cleared

Open-source MCP bridge that lets Claude search, read, and write FHIR R4 resources against any EHR or sandbox FHIR API with SMART-on-FHIR auth.

arXiv MCP Server

MCP server · blazickjp · GA · verified: works · security: cleared

Search and retrieve arXiv preprints (incl. q-bio) and metadata; part of the Literature Graph connector in Claude Science.

bio-research (Claude Code Plugin)

Claude Code Plugin · Anthropic · GA · verified: degraded · security: cleared

Umbrella plugin bundling 5 analysis skills and ~10 MCP connectors (PubMed, BioRender, ChEMBL, Synapse, Wiley, Open Targets, Benchling, etc.) for preclinical R&D.

cBioPortal (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Cancer genomics (TCGA et al.) via cBioPortal REST API.

cBioPortal MCP Server

MCP server · cBioPortal · GA · verified: works · security: caution

Query cancer genomics studies, mutations, and clinical data from cBioPortal; also the Cancer Models connector in Claude Science.

clinical-trial-protocol (Anthropic Healthcare Plugin)

Claude Code Plugin · Anthropic · GA · verified: works · security: caution

Anthropic Claude Code plugin that drafts FDA/NIH-compliant Phase 2/3 clinical-trial protocols for drugs or devices via a waypoint-based workflow.

eQTL Catalogue (Claude Science Connector)

Claude.ai Connector · Anthropic · GA · verified: works · security: cleared

Uniformly processed cis-QTL (eQTL/sQTL) summary statistics from EMBL-EBI’s eQTL Catalogue; a source in the Human Genetics connector in Claude Science.

fhir-developer (Anthropic Healthcare Plugin)

Claude Code Plugin · Anthropic · GA · verified: works · security: cleared

Anthropic Claude Code plugin for authoring FHIR R4 resources with LOINC, SNOMED, and RxNorm validation.

gnomAD (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

GnomAD v4 population variant frequencies via GraphQL API.

histolab (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Lightweight WSI tile extraction and preprocessing.

instrument-data-to-allotrope

Claude Skill · Anthropic · GA · verified: works · security: cleared

Converts 40+ lab-instrument output formats to Allotrope Simple Model JSON / CSV for LIMS and data-lake ingestion.

neuro-mcp

MCP server · AImplifier · Alpha · verified: works · security: caution

54-tool MCP server wrapping MNE-Python EEG/MEG preprocessing, source imaging, a BIDS/EHR record store, and offline interactive plots.

nextflow-development

Claude Skill · Anthropic · GA · verified: works · security: cleared

Runs nf-core rnaseq, sarek, and atacseq pipelines on local FASTQ or GEO/SRA inputs.

nnU-Net (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Medical image segmentation with nnU-Net’s self-configuring framework — auto-selects architecture, preprocessing, training for any modality.

openFDA (Claude Skill)

Claude Skill · SciAgent · GA · verified: works · security: cleared

Query openFDA REST API for adverse events (FAERS), labeling, product info, recalls, enforcement.

pacsomatic (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Operator toolkit for nf-core/pacsomatic matched tumor-normal workflows from BAM inputs.

prior-auth-review (Anthropic Healthcare Plugin)

Claude Code Plugin · Anthropic · GA · verified: works · security: caution

Anthropic Claude Code skill (in the consolidated healthcare plugin) that reviews prior-authorization request documents and surfaces gaps against payer rules.

pydicom (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Python library for working with DICOM (Digital Imaging and Communications in Medicine) files.

pyomop

MCP server · Bell Eapen · GA · verified: degraded · security: cleared

Python OMOP CDM toolkit that ships an MCP server, letting Claude inspect and run SQL against an OHDSI CDM database on SQLite, PostgreSQL or MySQL

scientific-problem-selection

Claude Skill · Anthropic · GA · verified: works · security: caution

Structured framework for research project ideation, risk assessment, and troubleshooting, based on Fischbach & Walsh (Cell 2024).

scikit-survival (Claude Skill)

Claude Skill · K-Dense · GA · verified: works · security: cleared

Comprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival.

scvi-tools

Claude Skill · Anthropic · GA · verified: works · security: cleared

Deep-learning workflows for scVI, scANVI, totalVI, MultiVI, PeakVI, DestVI, and related scvi-tools models for single-cell omics.

single-cell-rna-qc

Claude Skill · Anthropic · GA · verified: works · security: cleared

scverse MAD-based QC for .h5ad and 10x .h5 single-cell RNA-seq inputs.


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