Chemistry

Installable Claude components for cheminformatics, computational chemistry, chemical structure handling, reaction prediction, retrosynthesis, and chemistry-aware language interfaces.

Anthropic PubMed Connector

MCP server · Anthropic · GA

Anthropic-managed NCBI literature search via PubMed and PubMed Central.

AutoDock Vina (Claude Skill)

Claude Skill · SciAgent · GA

Molecular docking with AutoDock Vina (Python API).

BGPT Paper Search (Claude Skill)

Claude Skill · K-Dense · GA

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server.

BioContextAI Knowledgebase MCP

MCP server · BioContextAI · GA

Read-only MCP that unifies 14+ biomedical databases (Antibody Registry, UniProt, STRING, AlphaFold, KEGG, Open Targets) for immune and protein-context queries.

BioMCP

MCP server · GenomOncology · GA

Unified biomedical lookup across PubMed, ClinicalTrials.gov, MyVariant, and OpenFDA.

BioPython (Claude Skill)

Claude Skill · K-Dense · GA

Comprehensive molecular biology toolkit.

BioRender Connector

MCP server · BioRender · GA

Scientific-figure assembly from the 50,000+ BioRender icon and template library.

BioServices (Claude Skill)

Claude Skill · K-Dense · GA

Unified Python interface to 40+ bioinformatics services.

Biomni (Claude Skill)

Claude Skill · Stanford SNAP Lab · GA

General-purpose biomedical AI agent that plans and runs multi-step research workflows across genomics, drug discovery, and clinical analysis.

COBRApy (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill driving COBRApy for constraint-based metabolic modelling — FBA, FVA, gene knockouts, flux sampling, gapfilling on SBML genome-scale models.

ChEMBL Connector

Claude Code Plugin · EMBL-EBI (Anthropic-packaged) · GA

Anthropic-packaged plugin and Claude.ai connector over EMBL-EBI’s ChEMBL bioactive-compound database — compound, target, bioactivity, and mechanism-of-action lookup.

ChemCP

MCP server · Scott Reed · GA

MCP App that renders interactive 2D molecular structures from SMILES and computes basic properties inside Claude conversations via RDKit.js.

ChemLint

MCP server · molML (TU/e) · GA

MCP server exposing 150+ molecular machine-learning tools — SMILES cleaning, descriptors, similarity, clustering, model training — so Claude runs cheminformatics ML without Python scripting.

Composer

Plugin · Scripps AI Enablement · Beta

Turns a plain-language scientific problem into a grounded, runnable Claude solution composed from this catalog, reusing recipes and recommending autonomous systems.

Consensus Plugin

Claude Code Plugin · Consensus · GA

Consensus.app MCP plugin bringing AI-powered scientific literature search and evidence synthesis into Claude across all research areas.

CovaSyn Chemistry MCP

MCP server · CovaSyn · GA

Hosted deterministic cheminformatics MCP with 130+ tools spanning ADMET, docking, retrosynthesis, ICH M7 toxicology, NMR/MS, and biologics design.

Database Lookup (Claude Skill)

Claude Skill · K-Dense · GA

Search 78 public scientific, biomedical, materials science, and economic databases via REST APIs.

Datamol (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill wrapping Datamol — an RDKit-based Python library for molecular standardization, transformations, featurization, and parallel processing on large compound libraries.

DeepChem (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill driving DeepChem for molecular machine learning — graph neural nets (GCN, GAT, MPNN, AttentiveFP), featurization, and the MoleculeNet benchmarks (toxicity, ADMET, quantum properties).

DrugBank MCP Server

MCP server · openpharma-org (community) · GA

Community MCP server exposing a local DrugBank SQLite (17k+ drugs) with 16 query methods for repurposing, target lookup, interactions, and structural similarity.

Guide to Pharmacology (GtoPdb) (Claude Skill)

Claude Skill · SciAgent · GA

Query IUPHAR/BPS Guide to Pharmacology (GtoPdb) for receptor-ligand interactions, target/ligand metadata, families, and approved drugs.

Hypothesis Generation (Claude Skill)

Claude Skill · K-Dense · GA

Structured hypothesis formulation from observations.

Literature Review (Claude Skill)

Claude Skill · K-Dense · GA

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.).

MedChem (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill wrapping MedChem — drug-likeness filters (Lipinski, Veber, Egan, Muegge), ADMET-flag detection, and medicinal-chemistry alerts on top of RDKit.

Molecule-MCP

MCP server · chatmol · GA

MCP bundle letting Claude drive PyMOL and ChimeraX visualization and run GROMACS molecular dynamics simulations via natural language.

Molfeat (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill wrapping Molfeat — a unified API over 100+ molecular featurizers spanning classical fingerprints, descriptors, and pre-trained chemical foundation-model embeddings.

Paper Lookup (Claude Skill)

Claude Skill · K-Dense · GA

Search 10 academic paper databases via REST APIs for research papers, preprints, and scholarly articles.

PubChem MCP Server

MCP server · JackKuo666 · GA

MCP server that lets Claude query PubChem for compounds by name, SMILES, CID, or formula and pull structure files.

PyTDC (Claude Skill)

Claude Skill · K-Dense · GA

Claude skill driving PyTDC for Therapeutics Data Commons benchmarks — ADMET, drug-target / drug-drug interactions, drug response, molecular generation, retrosynthesis.

RDKit Cheminformatics Skill

Claude Skill · K-Dense · GA

Claude skill providing RDKit recipes for SMILES parsing, descriptors, fingerprints, substructure search, reactions, and 2D/3D molecular generation.

RDKit MCP Server

MCP server · TandemAI · GA

MCP server exposing the full RDKit API as discrete tool calls so Claude can run cheminformatics without executing Python locally.

Rowan

Claude Skill, MCP server · K-Dense / Rowan · GA

Cloud-native molecular modeling and medicinal-chemistry workflow platform, installable as a Claude Skill or an MCP server.

SAR Analysis (Claude Skill)

Claude Skill · SciAgent · GA

Structure-activity relationship (SAR) analysis guide for drug discovery including molecular descriptor analysis, scaffold analysis, and activity cliff detection

Scholar Gateway Connector (Wiley)

MCP server · Wiley · Beta

Wiley remote connector for peer-reviewed scholarly content — 3M+ articles, 300+ Life Sciences journals.

Scientific Brainstorming (Claude Skill)

Claude Skill · K-Dense · GA

Creative research ideation and exploration.

Scientific Critical Thinking (Claude Skill)

Claude Skill · K-Dense · GA

Evaluate scientific claims and evidence quality.

Synapse.org Connector

MCP server · Sage Bionetworks · GA

Discovery and metadata retrieval across Synapse-hosted biomedical datasets and consortium projects.

ToolUniverse

MCP server · Zitnik Lab (Harvard Medical School) · MIT Lincoln Laboratory · GA

Harvard / MIT MCP server bundling 600+ vetted scientific tools — literature, chemistry, omics, clinical trials — for AI-scientist-style hypothesis exploration.

TorchDrug (Claude Skill)

Claude Skill · K-Dense · GA

PyTorch-native graph neural networks for molecules and proteins.

UniChem (Claude Skill)

Claude Skill · SciAgent · GA

Cross-reference compound IDs across 20+ databases (ChEMBL, DrugBank, PubChem, ChEBI, PDB, SureChEMBL, HMDB, DrugCentral, BindingDB) via UniChem REST API.

ZINC (Claude Skill)

Claude Skill · SciAgent · GA

Query ZINC15/ZINC22 virtual compound libraries (1.4B compounds, 750M purchasable).

bio-research (Claude Code Plugin)

Claude Code Plugin · Anthropic · GA

Umbrella plugin bundling 5 analysis skills and ~10 MCP connectors (PubMed, BioRender, ChEMBL, Synapse, Wiley, Open Targets, Benchling, etc.) for preclinical R&D.

instrument-data-to-allotrope

Claude Skill · Anthropic · GA

Converts 40+ lab-instrument output formats to Allotrope Simple Model JSON / CSV for LIMS and data-lake ingestion.

matchms (Claude Skill)

Claude Skill · K-Dense · GA

Spectral similarity and compound identification for metabolomics.

scientific-problem-selection

Claude Skill · Anthropic · GA

Structured framework for research project ideation, risk assessment, and troubleshooting, based on Fischbach & Walsh (Cell 2024).

smina (Claude Skill)

Claude Skill · SciAgent · GA

Smina molecular docking CLI.


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