Chai-1 (Claude Skill)
Predicts biomolecular complex structures with Chai-1, driven as a Claude skill over local or hosted inference.
| Type | Claude Skill |
| Supplier | Chai Discovery |
| Availability | GA — Claude Science research skill |
| Pricing | Free / OSS (Apache-2.0, code + weights) |
| Capabilities | Read/Write — writes predicted complex structures with confidence scores |
| Verified | works · 2026-07-20 |
| Security | cleared · 2026-07-20 — provenance matches Chai Discovery, chaidiscovery/chai-lab Apache-2.0, no GitHub advisories |
How to install
- Claude Science — enable the built-in Chai-1 research skill (Anthropic-hosted; not published to the public
anthropics/life-sciencesmarketplace). - Run the model yourself — the upstream model is open source:
git clone https://github.com/chaidiscovery/chai-labFollow the repo README for environment setup and model weights.
What it does
Runs Chai-1 to predict structures of proteins, nucleic acids, and protein–ligand complexes. Optionally uses the hosted web server (lab.chaidiscovery.com) or an MSA server; otherwise fully local.
Primary use cases: Complex structure prediction, protein–ligand modelling, antibody/antigen modelling
Notes
Claude Science: Featured as a research skill in Anthropic’s Claude Science. Its inclusion there is an independent signal of quality and trustworthiness for life-science work.
Local or vendor-hosted (lab.chaidiscovery.com). GPU recommended for local runs.
Sources
Installed this tool?
Share feedback — install path, OS, errors, workarounds. The form opens with this tool pre-selected and a link back to this page.