Gene Ontology MCP Server

Exposes Gene Ontology terms and gene–function annotations to Claude via a community MCP server over the GO API.


Type	MCP server
Supplier	Augmented Nature
Availability	Beta — community OSS
Pricing	GO data is Free / CC BY 4.0; the MCP wrapper code is under a restrictive personal, non-commercial license (no redistribution/modification/commercial use without permission)
Capabilities	Read-only
Verified	works · 2026-07-20
Security	caution · 2026-07-20 — wrapper repo LICENSE is a restrictive non-commercial grant (GitHub NOASSERTION); GO API public read-only

How to install

Claude Code / Desktop — community MCP server (Augmented Nature, OSS):

git clone https://github.com/Augmented-Nature/GeneOntology-MCP-Server
cd GeneOntology-MCP-Server
npm install && npm run build
claude mcp add --transport stdio geneontology-server -- node /path/to/GeneOntology-MCP-Server/build/index.js

Claude Science — also available as the Genes & Ontologies featured connector (Anthropic-hosted; enable in Claude Science).
Public API — query directly at api.geneontology.org.

What it does

Look up GO terms and hierarchy, retrieve gene-product annotations, and gather inputs for functional enrichment via the Gene Ontology API.

Primary use cases: GO term lookup, functional annotation, enrichment input retrieval

Notes

Claude Science: Offered inside Anthropic’s Claude Science via the Genes & Ontologies featured connector. Its inclusion there is an independent signal of quality and trustworthiness for life-science research.

Community server over the public GO API (api.geneontology.org).

Sources

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