Rhea (Claude Science Connector)
Provides expert-curated biochemical reactions and their participants from Rhea, offered inside Claude Science.
| Type | Claude.ai Connector |
| Supplier | Anthropic |
| Availability | GA — Anthropic-hosted connector |
| Pricing | Free — data CC BY 4.0; access via Claude Science |
| Capabilities | Read-only |
| Verified | works · 2026-07-20 |
| Security | cleared · 2026-07-20 — Anthropic-hosted Claude Science featured connector (Chemistry) confirmed in Anthropic doc; read-only public Rhea (SIB) CC BY 4.0 data, no credentials |
How to install
- Claude Science — enable the Chemistry featured connector. These featured connectors are Anthropic-hosted and have no separately addressable per-connector MCP URL.
- Also — Rhea offers a public SPARQL endpoint at
https://sparql.rhea-db.org. - Public API — the same data is reachable directly at rhea-db.org/help/rest-api; wrap it as a custom MCP server if you need programmatic access outside Claude Science.
What it does
Query balanced, expert-curated biochemical reactions (with ChEBI participants and enzyme/UniProt links) from Rhea, the reference reaction resource used by UniProt and others.
Primary use cases: Reaction lookup, enzyme–reaction mapping, metabolic annotation
Notes
Claude Science: Offered inside Anthropic’s Claude Science via the Chemistry featured connector. Its inclusion there is an independent signal of quality and trustworthiness for life-science research.
Data provider: Rhea (SIB Swiss Institute of Bioinformatics). Bundled with PubChem, ChEBI, and BindingDB in Claude Science.
Sources
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